HUMAN LEUKEMIA BONE MARROW LYSATE
Leukemia Sample
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Diagnosis: Acute myeloid leukemia
   
Sex: Female
Age: 54
     
Catalog Number:

Extraction 1, soluble protein fraction

T18-016-T-1

Human Leukemia tumor tissue lysate

1 mg/ml, 100 µg/vial

 

Extraction 2, insoluble protein fraction

T18-016-T-2

Human Leukemia tumor tissue lysate

1 mg/ml, 100 µg/vial

PATHOLOGY DATA

  
Location:              Posterior iliac crest  
   
Hematology:

Leukocyte (WBC)

3.08 x 109 / L

 

Erythrocyte (RBC)

3.56 x 1012 / L

Lymphocyte

58.8%

 

Hemoglobin

10.4 g/dl

Neutrophil

33.4%

 

Hematocrit (PCV)

31 %

Eosinophil

0

 

Platelets

33 x 109 / L

Basophil

 

 

Blasts

95%

Monocyte

6.2%

 

 

 
   
Biochemistry:

LDH:

not done

 

Sodium (Na):

not done

Serum albumin:

not done

 

Potassium (K):

not done

Beta microglobulins:

not done

 

Chloride (Cl):

not done

Creatinin:

not done

 

Calcium (Ca):

not done

Creatinin clearance:

not done

 

Bicarbonate:

not done

Albuminuria:

not done

 

Glycemia:

not done
   
Microscopic appearance: Normochromic, anisocytosis. Pancytopenia. Erythropoiesis and myelopoiesis are markedly suppressed. Marrow is diffusely infiltrated with medium to large size blast. Blast has high N:C ratio, pale blue granular cytoplasm, irregular cellular outline, and open nuclear chromatin containing 2-3 nucleoli. Lymphocytes and plasma cells reduced. Megakaryocytes also reduced. No granuloma or lymphoid tissue seen.
   
Biological markers:

B cell marker:

CD20 (-), CD34 strong (+)

T cell marker:

CD3 (-), CD5 (-), CD10 (-), CD79a (-)

Other markers:

PAS negative

TdT:

Bright positive

Myeloperoxidase:

positive in 3% blasts

Nonspecific esterase:

 

Black Soudan:

 
   
Source:

Integrated Laboratory Services-Biotech (ILSbio), Chestertown, MD 21620 www.ilsbio.com
ILS-26434

     
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