HUMAN LEUKEMIA BONE MARROW LYSATE
Leukemia Sample
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Diagnosis: Acute lymphoblastic leukemia
   
Sex: Male
Age: 25
     
Catalog Number:

Extraction 1, soluble protein fraction

T18-001-T-1

Human Leukemia tumor tissue lysate

1 mg/ml, 100 µg/vial

 

Extraction 2, insoluble protein fraction

T18-001-T-2

Human Leukemia tumor tissue lysate

1 mg/ml, 100 µg/vial

PATHOLOGY DATA

  
Location:             

Posterior iliac crest

  
   
Hematology:

Leukocyte (WBC)

112 x 109 / L

 

Erythrocyte (RBC)

3.09 x 1012 / L

Lymphocyte

07%

 

Hemoglobin

7.6 g/dl

Neutrophil

05%

 

Hematocrit (PCV)

24%

Eosinophil

00%

 

Platelets

60 x 109 / L

Basophil

00%

 

Blasts

86%

Monocyte

00%

 

 

 
   
Biochemistry:

LDH:

326 µU / L

 

Sodium (Na):

139 meq / L

Serum albumin:

not done

 

Potassium (K):

4 meq / L

Beta microglobulins:

not done

 

Chloride (Cl):

101 meq / L

Creatinin:

0.5 mg / dl

 

Calcium (Ca):

not done

Creatinin clearance:

not done

 

Bicarbonate:

16 meq / L

Albuminuria:

negative

 

 

 
   
Microscopic appearance: Predominant cells are small sized, condensed nuclear chromatin with no visible nucleoli
   
Biological markers:

B cell marker:

CD79a (+), CD19 (+), CD34 (+), CD33 (-)

T cell marker:

CD3 (-), CD4 (-), CD5 (-), CD7 (-), CD8 (-), CD10 (+),

Other markers:

CD43 (-)

TdT:

 

Myeloperoxidase:

negative

Nonspecific esterase:

 

Black Soudan:

 
   
Comments:

CALLA positive precursor B-cell acute lymphoblastic leukemia
   
Cytogenetics: 18 cells were counted, all cells showed 46 chromosomes
   
Immunohistochemistry: Myeloperoxidase negative.
   
Source:

Integrated Laboratory Services-Biotech (ILSbio), Chestertown, MD 21620 www.ilsbio.com
ILS-22267

     
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