HUMAN BREAST TISSUE LYSATE

  
Diagnosis: Infiltrating ductal carcinoma.
   
Sex: Female
Age: 44
Grade: 2
Stage: IIB, T2N1M0  
Catalog Number:

Extraction 1, soluble protein fraction

T2-007-T-1

Human breast tumor tissue lysate

1 mg/ml, 100 µg/vial

T2-007-N-1

Human breast normal tissue lysate (matched)

1 mg/ml, 100 µg/vial

 

Extraction 2, insoluble protein fraction

T2-007-T-2

Human breast tumor tissue lysate

1 mg/ml, 100 µg/vial

T2-007-N-2

Human breast normal tissue lysate (matched)

1 mg/ml, 100 µg/vial

PATHOLOGY DATA

  
Location:              Left breast.  
   
Gross Findings:

Tumor size 4 cm, ill demarcated.

Cut section firm and white.

Ipsilateral axillary lymph nodes examined:      8
   
Microscopic findings: The tumor is composed of proliferation of malignant epithelial cells. The epithelial cells grown in the enlarged ducts contained comedo-necroses. The tumor cells have irregular, basophilic nuclei and abundant cytoplasm. Nuclear chromatin is coarse with prominent nuclei. Mitotic figures are abundant. Some areas show microinvasions.  The stroma is infiltrated by numerous inflammatory cells. The lymph nodes show metastasis.
   
Histologic pattern:

Cell distribution:

+/-

 

Structure / Pattern:

+/-

Diffuse:

-

 

Streaming:

-

Mosaic:

+

 

Storiform:

-

Necrosis:

-

 

Fibrosis:

-

Lymphocytic infiltration:

+

 

Pallisading:

-

Vascular invasion:

-

 

Cystic degeneration:

-

Clusterized:

+

 

Bleeding:

-

Alveolar formation:

+

 

Myxoid change:

-

Indian file:

-

 

Psammoma body:

-
   
Cellular differentiation:

Squamous:

+/-

 

Adenomatous:

+/-

 

Sarcomatous:

+/-

Squamoid:

-

 

Glandular cell:

+

 

Round cell:

-

Spindle:

-

 

Cell stratification:

+

 

Spindle cell:

-

Keratin:

-

 

Secretion:

+

 

Leiomyoblast:

-

Desmosome:

-

 

Intracellular vacuole:

+

 

Lipoblast:

-

Pearl:

-

 

Glandular formation:

+

 

Rhadomyoblast:

-
   
Nuclear atypia:

Nuclear Appearance:

0

I

II

III

Anisonucleosis:

 

X

 

 

Hyperchromatism:

 

X

 

 

Nucleolar prominent:

 

X

 

 

Multinucleated giant cell:

 

X

 

 

Mitotic activity:

 

X

 

 
   
Source:

Integrated Laboratory Services-Biotech  (ILSbio), Chestertown, MD 21620  www.ilsbio.com
ILS-1461

     
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